Kinetic Analysis of Hepatic Metabolism Using Hyperpolarized Dihydroxyacetone
نویسندگان
چکیده
منابع مشابه
Real-time detection of hepatic gluconeogenic and glycogenolytic states using hyperpolarized [2-13C]dihydroxyacetone.
Glycogenolysis and gluconeogenesis are sensitive to nutritional state, and the net direction of flux is controlled by multiple enzymatic steps. This delicate balance in the liver is disrupted by a variety of pathological states including cancer and diabetes mellitus. Hyperpolarized carbon-13 magnetic resonance is a new metabolic imaging technique that can probe intermediary metabolism nondestru...
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15 صفحه اولReal-Time Estimates of Hepatic Gluconeogenesis 1 Real-Time Detection of Hepatic Gluconeogenic and Glycogenolytic States Using Hyperpolarized [2- C]Dihydroxyacetone*
Glycogenolysis and gluconeogenesis are sensitive to nutritional state and the net direction of flux is controlled by multiple enzymatic steps. This delicate balance in the liver is disrupted by a variety of pathological states including cancer and diabetes mellitus. Hyperpolarized (HP) carbon-13 magnetic resonance (MR) is a new metabolic imaging technique that can probe intermediary metabolism ...
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ژورنال
عنوان ژورنال: Journal of Chemical Information and Modeling
سال: 2019
ISSN: 1549-9596,1549-960X
DOI: 10.1021/acs.jcim.8b00745